A Core-Shell Amino-Functionalized Magnetic Molecularly Imprinted Polymer Based on Glycidyl Methacrylate for Dispersive Solid-Phase Microextraction of Aniline

A core-shell amino-functionalized glycidyl methacrylate magnetic molecularly imprinted polymer (MIP) was synthesized by the suspension polymerization/surface imprinting method and characterized Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), mercury porosimetry, nitrogen gas adsorption–desorption, elemental analysis. This MIP used as sorbent in dispersive solid-phase microextraction (DSPME) of aniline from textile wastewater prior to high-performance liquid chromatography-mass spectrometry (HPLC-MS) measurements. Since is toxic a probable human carcinogen, its determination water great significance. challenging task because usually present at trace levels. The effects different DSPME variables on preconcentration efficiency have been studied using Plackett–Burman screening design experiments (DoE) followed response surface methodology optimization Box-Behnken design. Thus, DoE enabled investigation several simultaneously. Under optimized conditions, effectively selectively separated small amount detected real samples. detection limit 1 ng mL?1 attained, with good linearity acceptable recovery precision. results showed that could be reliable for efficiently analyzing